Chromatographic Quantification of Isoflavones (why and How)
نویسندگان
چکیده
Recent advances in chromatographic analysis of isoflavones, which can reach physiologically significant concentrations in human body fluids as a result of nutrition with food containing soy products or diet supplementation with phytoestrogen preparations, are surveyed and evaluated. Soy-derived food products and nutraceuticals are claimed to be beneficial for cardiovascular health and bone metabolism and to contribute signifycantly to cancer chemoprevention. Because clinical trials involving plantderived isoflavone-rich materials have been rather inconclusive, it seems important to discuss analytical means by which pharmacokinetic and pharmacodynamic data are generated.
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